For those of you who are MacBook Pro users, you too may have felt the pain from the somewhat oddly placed keyboard. From day one I thought it was too far away from the bottom of the machine. And while thin, the MBP doesn't have the ergonomic profile that you get with a Thinkpad. Enter the MacBook Air and you will see immediately that your wrists get to relax a bit more and don't strain nearly as hard to stay on the keyboard.
A week into the MB Air and I can honestly say that I have almost no pain or fatigue in my wrists when I use the machine standalone. In fact it's possibly more comfortable then using a regular keyboard...TBD for the moment.
I know a few other carpal tunnel sufferers--both of whom, like myself went to hand doctors and had all sorts of x-rays etc. (Zack@MySQL and Raven@451) so I will see what the other guys have to say. For me, so far, so good.